PT-141 – Research-Grade Cyclic Melanocortin Peptide
PT-141 (also known as bremelanotide) is a synthetic cyclic peptide derived from the melanocortin signaling framework and structurally related to α-melanocyte-stimulating hormone (α-MSH). Its defined amino acid substitutions and cyclized backbone distinguish it from linear melanocortin peptides. In laboratory research settings, PT-141 is utilized as a reference material for studying melanocortin receptor interaction models, peptide–receptor binding behavior, and comparative structure–activity relationships within melanocortin signaling pathways.
The cyclic structure of PT-141 introduces conformational constraints that influence stability and receptor engagement in vitro. This characteristic enables researchers to examine the impact of peptide cyclization on signaling specificity, binding dynamics, and degradation behavior without the complexity of larger protein-based systems. Its defined sequence and reproducible synthesis support controlled use in mechanistic assays, receptor interaction studies, and exploratory biochemical research conducted under controlled laboratory conditions.
Related research compounds
Melanotan 1 (MT-1) · Melanotan 2 (MT-2) · Kisspeptin-10 · Oxytocin · Gonadorelin
Documentation and methods
Analytical testing · How to read a COA · Batch COAs · Storage and handling · What are research peptides
Research guide PT-141 — structure, classification and analytical characterization
Important Information About This Research Product
- 1 Your vials are not empty. The lyophilized material may collect at the bottom of the vial and can appear minimal prior to inspection.
- 2 All products are supplied as lyophilized (freeze-dried) powder and require reconstitution. Bacteriostatic water is not supplied.
- 3 Store in a dry, cool, and dark environment away from UV exposure. For optimal preservation, storage at approximately 4°C is recommended.
- 4 This material is strictly for laboratory and research use only. No instructions regarding reconstitution, dosing, or administration can be provided.
