Melanotan 1 (MT-1)

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Melanotan I (MT-1) – Research-Grade Synthetic Melanocortin Peptide

Melanotan I (MT-1), also known as afamelanotide, is a synthetic linear peptide analog derived from the endogenous melanocortin sequence α-MSH. This compound incorporates defined terminal modifications that distinguish it from native melanocyte-stimulating hormone fragments. In laboratory research settings, Melanotan I is utilized as a reference material for studying melanocortin receptor interactions, peptide–receptor binding specificity, and structure–activity relationships within melanocortin signaling systems.

Unlike cyclic melanocortin peptides, Melanotan I retains a linear backbone, which imparts distinct physicochemical and conformational properties in vitro. This structural characteristic allows researchers to examine receptor engagement, peptide stability, and comparative signaling behavior without the constraints introduced by peptide cyclization. Its defined amino acid sequence and synthetic consistency support controlled use in mechanistic assays, receptor interaction studies, and exploratory biochemical research conducted under controlled laboratory conditions.

Related research compounds

Melanotan 2 (MT-2) · PT-141 · Kisspeptin-10 · Oxytocin · Gonadorelin

Documentation and methods

Analytical testing · How to read a COA · Batch COAs · Storage and handling · What are research peptides

Important Information About This Research Product

  1. 1 Your vials are not empty. The lyophilized material may collect at the bottom of the vial and can appear minimal prior to inspection.
  2. 2 All products are supplied as lyophilized (freeze-dried) powder and require reconstitution. Bacteriostatic water is not supplied.
  3. 3 Store in a dry, cool, and dark environment away from UV exposure. For optimal preservation, storage at approximately 4°C is recommended.
  4. 4 This material is strictly for laboratory and research use only. No instructions regarding reconstitution, dosing, or administration can be provided.
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