MOTS-c – Research-Grade Mitochondrial-Derived Peptide (16 Amino Acids)
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a synthetic research analog of an endogenous mitochondrial-derived peptide consisting of 16 amino acid residues. Encoded within mitochondrial DNA, MOTS-c is structurally distinct from nuclear-encoded peptides and proteins. In laboratory research settings, MOTS-c is utilized as a reference material for studying mitochondrial signaling models, peptide-mediated metabolic pathway interactions, and sequence-specific biochemical behavior associated with mitochondrial-derived peptides.
Due to its short, linear structure and absence of disulfide bonds, MOTS-c exhibits physicochemical properties that differ from larger mitochondrial proteins and multi-domain signaling molecules. This simplicity allows researchers to examine peptide stability, intracellular interaction models, and degradation dynamics in vitro without confounding structural complexity. Its defined amino acid sequence and consistent synthetic profile support controlled use in mechanistic assays, comparative peptide studies, and exploratory biochemical research conducted under controlled laboratory conditions.
Related research compounds
Humanin · SS-31 · NAD+ · Epitalon · FOXO4-DRI · L-Glutathione (GSH)
Documentation and methods
Analytical testing · How to read a COA · Batch COAs · Storage and handling · What are research peptides
Research guide MOTS-c — structure, classification and analytical characterization
Important Information About This Research Product
- 1 Your vials are not empty. The lyophilized material may collect at the bottom of the vial and can appear minimal prior to inspection.
- 2 All products are supplied as lyophilized (freeze-dried) powder and require reconstitution. Bacteriostatic water is not supplied.
- 3 Store in a dry, cool, and dark environment away from UV exposure. For optimal preservation, storage at approximately 4°C is recommended.
- 4 This material is strictly for laboratory and research use only. No instructions regarding reconstitution, dosing, or administration can be provided.
